Research progress of biosensors for detection of SARS-CoV-2 variants based on ACE2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 변종, 치료기술, [키워드] Accuracy ACE2 acute respiratory syndrome addition antibody biosensor biosensors caused Cell cells complex coronavirus coronavirus disease COVID-19 detect detection Diagnosis drug evaluated gold standard Health increase Interaction modulate Mutation Novel coronavirus pandemic Prevent receptor RT-PCR SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2. the spike protein time-consuming variants Variation virus virus mutations [DOI] 10.1016/j.talanta.2022.123813 PMC 바로가기
A comprehensive review of SARS-CoV-2 vaccines: Pfizer, Moderna & Johnson & JohnsonSARS-CoV-2 백신에 대한 포괄적인 검토: Pfizer, Moderna & Johnson & JohnsonReview Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] Adenovirus administration age approval clinical clinical trial clinical trials coronavirus coronavirus. COVID-19 COVID-19 vaccine COVID-19 vaccines effective Efficacy General population group Johnson Johnson & Johnson Johnson & large cohort mechanism moderate Moderna mRNA vaccines Novel coronavirus ongoing trial ongoing trials outbreak pandemic participant Pfizer Safety SARS-CoV-2 SARS-CoV-2 coronavirus SARS-COV-2 infection shown Side effects Spike protein symptomatic SARS-CoV-2 infection tested the SARS-CoV-2 the spike protein the United State Trial United States Vaccinations Vaccine vaccine administration variant [DOI] 10.1080/21645515.2021.2002083 PMC 바로가기 [Article Type] Review
Structure-based neutralizing mechanisms for SARS-CoV-2 antibodiesArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, [키워드] antibody Antibody structure caused consequence COVID-19 pandemic Critical cryo-EM develop effective effort epitope Host Infection mAbs mechanism molecular monoclonal antibody Neutralizing neutralizing antibody neutralizing mechanism pan-coronavirus vaccine. provide public health SARS-CoV-2 SARS-CoV-2 antibody Scientific community the spike protein Vaccine Vaccines [DOI] 10.1080/22221751.2022.2125348 PMC 바로가기
Pathogen-host adhesion between SARS-CoV-2 spike proteins from different variants and human ACE2 studied at single-molecule and single-cell levelsArticle Published on 2022-12-012022-11-16 Journal: Emerging Microbes & Infections [Category] SARS, 변종, 유전자 메커니즘, [키워드] ACE2 ACE2-RBD acute respiratory syndrome addition adhere binding complex coronavirus Delta delta variant destabilized effective force spectroscopy highest host cell human ACE2 human Angiotensin-converting enzyme immunization Infection inhibit Interaction investigated molecular dynamics molecular mechanism monoclonal antibody Mutation mutations N501Y Neutralizing neutralizing antibody omicron pathogen-host adhesion. Probability produced RBD Receptor binding domain S477N SARS-CoV-2 SARS-CoV-2 spike protein single-cell single-cell level Spike protein tested the spike protein variant variants virus wild type [DOI] 10.1080/22221751.2022.2128887 PMC 바로가기
Initial introduction and spread of the SARS-CoV-2 AY.4.2.1 Delta variant in Bulgaria, a genomic insightArticle Published on 2022-12-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] A222V accelerated Bulgaria COVID-19 pandemic delta variant dissemination Epidemiology Evolution genomic Mutation mutation/mutation rate. mutations raise SARS Coronavirus SARS-CoV-2 variant Spread the SARS-CoV-2 the spike protein Transmission United Kingdom variant [DOI] 10.1002/jmv.28033 PMC 바로가기
Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2Article Published on 2022-12-012022-11-16 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] change changes in Characteristics circulating cleavage contribute contributing to demonstrated dependent on determinant endosomal entry endosomal entry pathway endosomal pathway Entry facilitate feature Fusogenicity H655Y identify increase investigated less Mutation omicron Omicron BA.1 and BA.2 Pathogenesis pathogenicity plasma membrane predominant Proteases recent reduce reduced retained SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 WT serine protease spike spike mutation Spike protein spike protein cleavage. subsequent the spike protein TMPRSS2 transmembrane serine protease Virological virus entry [DOI] 10.1080/22221751.2022.2117098 PMC 바로가기
Monoclonal antibody therapies against SARS-CoV-2Article Published on 2022-11-012022-11-15 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antibody authorisation B.1.1.529 baseline clinical trial COVID-19 pandemic Immune escape intrinsic limitation mAb mAbs monoclonal antibody therapy outcome outcomes pandemic SARS-CoV-2 the spike protein therapeutic agents treatment strategy variant [DOI] 10.1016/S1473-3099(22)00311-5 PMC 바로가기
Seroprevalence of infection-induced SARS-CoV-2 antibodies among health care users of Northern Italy: results from two serosurveys (October-November 2019 and September-October 2021)Article Published on 2022-11-012022-11-15 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, 치료기술, [키워드] 95% CI 95% confidence interval age anti-Nucleocapsid IgG antibodies antibody calculated Care circulating CIs conducted COVID-19 detect domains enzyme-linked immunosorbent enzyme-linked immunosorbent assay Gender groups Health Hypothesis IgG IgG antibody Immunoglobulin immunosorbent Italy multiplex nucleocapsid Piedmont positive test result prevalence rate proportion Receptor binding domain Result S1 and S2 S1 domain Sample SARS-CoV-2 SARS-CoV-2 antibody semiquantitative method sera Seroprevalence seroprevalence. Serosurvey Support tested the spike protein Transmission dynamics virus [DOI] 10.1016/j.ijid.2022.09.017 PMC 바로가기
Rapid and universal detection of SARS-CoV-2 and influenza A virus using a reusable dual-channel optic fiber immunosensorArticle Published on 2022-11-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 신종인플루엔자, 치료기술, [키워드] clinical sample colloidal gold Delta demonstrated detect dual-channel optic fiber immunosensor enzyme-linked immunosorbent Evanescent fiber H1N1 H3N2 H7N9 Infectious disease influenza A influenza A virus influenza A virus limit of detection linear mobile phase detection. much higher omicron optical pathogenic viruses platform presenting Rapid Real-time monitoring respond SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 pseudovirus sensitivity specificity Strains Surveillance TCID the epidemic the SARS-CoV-2 the spike protein variants viruses [DOI] 10.1002/jmv.28015 PMC 바로가기
Prevalence of antibodies against SARS-CoV-2 in the Norwegian population, August 2021Article Published on 2022-11-012022-11-15 Journal: Influenza and Other Respiratory Viruses [Category] COVID19(2023년), SARS, 진단, [키워드] absence age Anti-nucleocapsid antibodies antibody automatically children collected conducted confirmed COVID-19 case contributed COVID-19 COVID-19 case COVID-19 pandemic COVID-19 vaccination CrI cross-sectional cumulative estimate Estimated flow cytometric IgG antibody individual Infection Laboratory National Norway nucleocapsid nucleocapsid protein Prevalence RBD Receptor binding domain registry data residual SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 seroprevalence sera seropositive sample Seroprevalence the spike protein vaccination vaccination. were measured women [DOI] 10.1111/irv.13024 PMC 바로가기